May 22nd
- 1818 – Jeremiah Boyle born.
- 1877 – Baden-Baden won the 3rd Kentucky Derby.
- 1905 – Laura Miller Derry born.
- 1914 – William Jackson Worthington died, aged 80.
- 1955 – Lena Madesin Phillips died, aged 73.
- 1964 – Historical Marker - 672 "Aunt Julia" Marcum dedicated in Williamsburg.
- 1986 – Collin Cowgill born.