September 22nd
- 1758 – John Caldwell born.
- 1795 – John P. Gaines born.
- 1823 – John Duncan Young born.
- 1835 – William Wirt Culbertson born.
- 1859 – Mathilde Brundage born.
- 1862 – William J. Dodd born.
- 1864 – Thomas Francis Marshall died, aged 63.
- 1869 – George Wood Monroe died, aged 64.
- 1870 – Michael Riley Powers born.
- 1872 – Garrett Davis died, aged 71.
- 1872 – Garrett Davis left office as US Senator from Kentucky.
- 1884 – Grover Land born.
- 1922 – Milt Ticco born.
- 1956 – Jesse Tannehill died, aged 82.
- 2005 – Lee Huber died, aged 86.